--- title: FDA gives green light to PTSD marijuana study in veterans description: FDA approves a long-delayed study to test marijuana for treating PTSD in veterans, allowing self-titration and high-potency cannabis, opening doors for future research. image: https://420intel.com/hubfs/AI-Generated%20Media/Images/An%20image%20of%20a%20clinical%20trial%20testing%20whether%20smoking%20marijuana%20can%20treat%20PTSD%20in%20veterans%2c%20authorized%20by%20the%20FDA%20after%20years%20of%20negotiations%20and%20objec.jpeg --- [![420intel.com](https://420intel.com/hs-fs/hubfs/Asset%2016-1.png?width=300&height=162&name=Asset%2016-1.png "420intel.com")](https://420intel.com) - [Home](https://420intel.com) - [Advertise](https://420intel.com/advertise) - [Directory](https://420intel.com/directory) - [Topics](https://420intel.com/blog) - [Recreational News](https://420intel.com/blog/tag/recreational-cannabis-news) - [Business News](https://420intel.com/tag/cannabis-business-news) - [Politics](https://420intel.com/tag/cannabis-politics) - [Technology](https://420intel.com/tag/cannabis-technology-news) - [Research](https://420intel.com/tag/medical-cannabis-news) - [Contact](https://420intel.com/contact-us) - [Follow us on Facebook](https://www.facebook.com/420intel) - [Follow us on LinkedIn](https://www.linkedin.com/company/420-intel/) - [Follow us on Twitter](https://x.com/420intel) - [Follow us on Instagram](https://www.instagram.com/420intel) ### Press ESC to close [![420intel.com](https://420intel.com/hs-fs/hubfs/Asset%2016-1.png?width=300&height=162&name=Asset%2016-1.png "420intel.com")](https://420intel.com) - [Home](https://420intel.com) - [Advertise](https://420intel.com/advertise) - [Directory](https://420intel.com/directory) - [Topics](https://420intel.com/blog) - [Recreational News](https://420intel.com/blog/tag/recreational-cannabis-news) - [Business News](https://420intel.com/tag/cannabis-business-news) - [Politics](https://420intel.com/tag/cannabis-politics) - [Technology](https://420intel.com/tag/cannabis-technology-news) - [Research](https://420intel.com/tag/medical-cannabis-news) - [Contact](https://420intel.com/contact-us) - [Follow us on Facebook](https://www.facebook.com/420intel) - [Follow us on LinkedIn](https://www.linkedin.com/company/420-intel/) - [Follow us on Twitter](https://x.com/420intel) - [Follow us on Instagram](https://www.instagram.com/420intel) # FDA gives green light to PTSD marijuana study in veterans - [![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=80&height=80&name=Buzz-No%20Outline-2.png) Buzz](https://420intel.com/blog/author/buzz) - [Medical Cannabis News](https://420intel.com/blog/tag/medical-cannabis-news) - 22 November 2024 The Food and Drug Administration (FDA) this week authorized a long-delayed clinical trial to test whether smoking marijuana can be used to treat post-traumatic stress disorder (PTSD) in veterans.  The trial, sponsored by the nonprofit Multidisciplinary Association for Psychedelic Studies (MAPS), has been blocked by the FDA since 2021. The agency had raised a variety of objections, including that allowing people to inhale high-potency cannabis was dangerous to their health.  The FDA also objected to the study’s “self-titration” dosing method, which will allow participants to smoke as much cannabis as they feel they need to relieve their symptoms up to a daily limit.  But on Wednesday, MAPS announced that the FDA will allow the trial to proceed. Importantly, they said the FDA no longer objects to either smoking or letting participants choose their preferred amount.  “After three years of negotiations with the FDA, this decision opens the door to future research into cannabis as a medical treatment, offering hope to millions,” the organization said in a statement.  FDA also will allow the trial to use a THC potency that matches commercially available cannabis in states permitting legal medical or recreational adult use.   One requirement the agency insisted on was that the study participants must have “prior experience” inhaling cannabis.  Allison Coker, director of cannabis research at MAPS, said they did not want to change the study design to fit how the FDA has historically viewed marijuana research. The trial is meant to mimic how veterans may use cannabis in their daily lives, the way it’s delivered and the amount that’s delivered.    Medical marijuana is legal in 39 states, and 24 states and D.C. have legalized recreational use. But marijuana is illegal federally, and long-standing restrictions on marijuana research presented hurdles.   Most cannabis users are smoking or vaping, Coker said, which the FDA was reluctant to allow. But smoking or vaping means the effects happen almost instantly, which is important for people who have PTSD.  Additionally, the available products in states where marijuana is legal are of a much higher potency than what the federal government has until very recently allowed to be used in studies.   Despite the growing use of cannabis among patients with PTSD, there have been limited rigorous studies on whether it works.  “People are using it for medical use. States are clearing it for medical use, but the FDA has not weighed in on it. We don’t have as many studies and data as we might want, especially we don’t have studies \[reflecting\] the way that people are using it in the states,” Coker said.  Coker said the approval shows the federal government is slowly coming around to recognizing the value of research into the potential benefits of marijuana rather than its harms.  The changing legal landscape of marijuana prompted the Biden administration to propose rescheduling the drug as a lower risk, which could ease some of the existing restrictions. But the process is long and complex, and it’s not clear if the incoming Trump administration will continue it.  Still, the Department of Health and Human Services, in a report to Congress this summer, acknowledged long-standing federal barriers to researching marijuana and indicated that better research is needed.  The MAPS study will be funded by a $12.9 million grant from Michigan’s cannabis agency, which devotes taxes from retail marijuana sales to fund research into the drug’s health benefits.   The randomized, placebo-controlled study will enroll 320 veterans suffering from moderate to severe PTSD. Researchers will use marijuana from Canada with a high level of THC that closely matches the legal products sold domestically, Coker said.  Coker said the hope is their approval was a tipping point. The group published all their FDA correspondence online so other researchers can learn from it.  “Our goal was really to help lift up research across the field. That’s why this was so important to us to have this fight,” Coker said.     [by The Hill](https://thehill.com/policy/healthcare/5003532-fda-gives-green-light-to-ptsd-marijuana-study-in-veterans/) [Medical Cannabis News](https://420intel.com/blog/tag/medical-cannabis-news) ![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=200&height=200&name=Buzz-No%20Outline-2.png) #### [Buzz](https://420intel.com/blog/author/buzz) At 420 Intel, we cover cannabis legalization news throughout the world, offer reliable information for cannabis business owners, detail technological advances that impact the marijuana industry, cover marijuana rallies from across the globe, and everything in between. - - - [Cannabis Politics](https://420intel.com/blog/tag/cannabis-politics) [![Montana’s Senate election complicates Cannabis legislation](https://420intel.com/hs-fs/hubfs/Imported_Blog_Media/Montana%E2%80%99s%20Senate%20election%20complicates%20Cannabis%20legislation.jpg?width=550&height=395&name=Montana%E2%80%99s%20Senate%20election%20complicates%20Cannabis%20legislation.jpg)](https://420intel.com/blog/montanas-senate-election-complicates-cannabis-legislation) - [Admin](https://420intel.com/blog/author/admin) - 7 March 2024 #### [Montana’s Senate election complicates Cannabis legislation](https://420intel.com/blog/montanas-senate-election-complicates-cannabis-legislation) Democrats are accusing Republicans of playing politics with a package of veterans bills spearheaded... [Cannabis Laws](https://420intel.com/blog/tag/cannabis-laws) [![Germany Dilutes Plan To Legalize Cannabis](https://420intel.com/hs-fs/hubfs/AdobeStock_226382495.jpeg?width=550&height=395&name=AdobeStock_226382495.jpeg)](https://420intel.com/blog/germany-dilutes-plan-to-legalize-cannabis) - [![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=80&height=80&name=Buzz-No%20Outline-2.png) Buzz](https://420intel.com/blog/author/buzz) - 7 November 2025 #### [Germany Dilutes Plan To Legalize Cannabis](https://420intel.com/blog/germany-dilutes-plan-to-legalize-cannabis) BERLIN, April 12 (Reuters) – Germany has taken a significant step in its mission to **legalize...** [Medical Cannabis News](https://420intel.com/blog/tag/medical-cannabis-news) [![Michigan Bill Could Legalize Psychedelic Mushrooms For PTSD Treatment](https://420intel.com/hs-fs/hubfs/AdobeStock_789455840.jpg?width=550&height=395&name=AdobeStock_789455840.jpg)](https://420intel.com/blog/michigan-bill-could-legalize-psychedelic-mushrooms-for-ptsd-treatment) - [![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=80&height=80&name=Buzz-No%20Outline-2.png) Buzz](https://420intel.com/blog/author/buzz) - 1 October 2024 #### [Michigan Bill Could Legalize Psychedelic Mushrooms For PTSD Treatment](https://420intel.com/blog/michigan-bill-could-legalize-psychedelic-mushrooms-for-ptsd-treatment) ## A new Michigan bill seeks to legalize psychedelic mushrooms for PTSD treatment, allowing adults to... - [Follow us on Facebook](https://www.facebook.com/420intel) - [Follow us on LinkedIn](https://www.linkedin.com/420intel) - [Follow us on Twitter](https://twitter.com/420intel) - [Follow us on Instagram](https://www.instagram.com/420intel) Back to Top ```json { "@context" : "https://schema.org", "@type" : "BlogPosting", "author" : { "@type" : "Person", "name" : "Buzz", "url" : "https://420intel.com/blog/author/buzz" }, "dateModified" : "2024-11-22T13:47:46.672Z", "datePublished" : "2024-11-22T13:47:46.000Z", "headline" : "FDA gives green light to PTSD marijuana study in veterans", "image" : [ "https://420intel.com/hubfs/AI-Generated%20Media/Images/An%20image%20of%20a%20clinical%20trial%20testing%20whether%20smoking%20marijuana%20can%20treat%20PTSD%20in%20veterans%2c%20authorized%20by%20the%20FDA%20after%20years%20of%20negotiations%20and%20objec.jpeg" ], "mainEntityOfPage" : { "@id" : "https://420intel.com/blog/fda-gives-green-light-to-ptsd-marijuana-study-in-veterans", "@type" : "WebPage" }, "publisher" : { "@type" : "Organization", "logo" : { "@type" : "ImageObject", "url" : "https://420intel.com/hubfs/Asset%2016.png" }, "name" : "420 Intel" } } ```