---
title: Cannabis-Based Drug Significantly Reduces Back Pain
description: Experimental cannabis-based drug shows promise in reducing chronic back pain, offering a safer alternative to opioids and NSAIDs.
image: https://420intel.com/hubfs/gras-grun-X1uq0SqsTVs-unsplash.jpg
---

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# Cannabis-Based Drug Significantly Reduces Back Pain

- [![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=80&height=80&name=Buzz-No%20Outline-2.png) Buzz](https://420intel.com/blog/author/buzz)
- [Medical Cannabis News](https://420intel.com/blog/tag/medical-cannabis-news)
- 1 October 2025

A new study has found that an experimental **cannabis-based drug** may provide meaningful relief for patients suffering from chronic back pain. The clinical trial, which involved 800 patients, is adding weight to the growing body of research highlighting the therapeutic potential of cannabis for pain management.

The research, conducted by German drugmaker Vertanical, tested a proprietary liquid extract that combines cannabinoids in carefully controlled doses. Unlike over-the-counter medications or opioids, this **cannabis-based drug** was shown to reduce pain without the same risks of dependence or abuse that have long plagued traditional painkillers.

How the Cannabis-Based Drug Works

Unlike Epidiolex, an FDA-approved treatment for rare epileptic seizures that contains only CBD, Vertanical’s new formula includes microdosed THC—the psychoactive compound in cannabis. The amount is so small that patients did not experience intoxication. This makes the **cannabis-based drug** unique, as it balances therapeutic cannabinoids while minimizing unwanted side effects.

Patients in the study reported improvements not only in pain levels but also in sleep quality and physical function. After 12 weeks, those taking the **cannabis-based drug** reported a nearly two-point reduction in pain on an 11-point scale, compared with just 1.4 points in the placebo group.

Why a Cannabis-Based Drug Matters

 

Traditional treatments like ibuprofen and opioids carry risks—NSAIDs can damage the stomach, while opioids are tied to addiction and overdose. A safe and effective **cannabis-based drug** could offer patients a new pathway to relief.

Dr. Matthias Karst, lead author of the study and a pain specialist at Hannover Medical School, explained that this breakthrough shows cannabis “can significantly reduce pain and improve physical function without the safety concerns of opioids.” The results, published in *Nature*, have drawn global attention.

Next Steps for Approval

Vertanical has already filed an application for its **cannabis-based drug** with European regulators. In the U.S., the company is working with the FDA to design clinical trials that could eventually lead to approval. If successful, this **cannabis-based drug** could become one of the first widely prescribed cannabinoid-based medications for chronic back pain.

Final Thoughts

With opioid addiction still a national crisis and millions seeking safer alternatives for pain management, the promise of a **cannabis-based drug** is significant. As more research emerges, patients and healthcare providers alike are watching closely. If approved, this innovation could redefine how chronic pain is treated and further validate the role of cannabis in modern medicine.

 

[by Fast Company](https://www.fastcompany.com/91412708/cannabis-based-drug-reduces-back-pain-nature-study)

[Medical Cannabis News](https://420intel.com/blog/tag/medical-cannabis-news) [Medical Marijuana News](https://420intel.com/blog/tag/medical-marijuana-news)

![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=200&height=200&name=Buzz-No%20Outline-2.png)

#### [Buzz](https://420intel.com/blog/author/buzz)

At 420 Intel, we cover cannabis legalization news throughout the world, offer reliable information for cannabis business owners, detail technological advances that impact the marijuana industry, cover marijuana rallies from across the globe, and everything in between.

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- [![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=80&height=80&name=Buzz-No%20Outline-2.png) Buzz](https://420intel.com/blog/author/buzz)
- 28 August 2025

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- [![Buzz](https://420intel.com/hs-fs/hubfs/Buzz-No%20Outline-2.png?width=80&height=80&name=Buzz-No%20Outline-2.png) Buzz](https://420intel.com/blog/author/buzz)
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